Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10948793 | 0.78 | CYP3A4 (0.50) | CYP3A4RAPGEF4MAPTSMN1; SMN2MEN1 | |
| SCHEMBL8772397 | 0.76 | CYP3A4 (0.48) | CYP3A4RAPGEF4MAPTSMN1; SMN2GAA | |
| SCHEMBL18663454 | 0.75 | TSHR (0.43) | CYP3A4MAPTGAANPC1RAB9A | |
| SCHEMBL22688977 | 0.74 | ALDH1A1 (0.44) | CYP3A4MAPTSMN1; SMN2GAANPC1 | |
| SCHEMBL27350577 | 0.74 | CYP3A4 (0.52) | CYP3A4RAPGEF4MAPTGAANPC1 | |
| SCHEMBL29838199 | 0.72 | APEX1 (0.41) | MAPTSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL21102094 | 0.72 | HTT (0.34) | HTTSLC6A2 | |
| SCHEMBL20345815 | 0.71 | EPHX2 (0.49) | CYP3A4SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL12749869 | 0.71 | CYP3A4 (0.43) | CYP3A4RAPGEF4MAPTSMN1; SMN2NPC1 | |
| SCHEMBL19361101 | 0.70 | LMNA (0.42) | MAPTSMN1; SMN2NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076166-A2 | OXIMYL HCV SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2009-06-18 | — | — | WO | disclosed |
| WO-2009076173-A2 | FLUORINATED TRIPEPTIDE HCV SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2009-06-18 | — | — | WO | disclosed |