Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8036317 | 0.90 | MAPK1 (0.45) | SMN1; SMN2MAPK1KMT2ATP53HTT | |
| SCHEMBL8034026 | 0.87 | MAPK1 (0.47) | SMN1; SMN2MAPK1KMT2ATP53HTT | |
| SCHEMBL8030236 | 0.87 | MAPK1 (0.48) | SMN1; SMN2MAPK1KMT2ATP53HTT | |
| SCHEMBL8031868 | 0.87 | PPIB (0.38) | GAASMN1; SMN2MAPK1KMT2ATP53 | |
| SCHEMBL8034113 | 0.86 | SMN1; SMN2 (0.40) | GAABDKRB2SMN1; SMN2MCHR1KMT2A | |
| SCHEMBL8036207 | 0.85 | GRM5 (0.38) | GAASMN1; SMN2MAPK1KMT2ATP53 | |
| SCHEMBL8030648 | 0.85 | KMT2A (0.36) | SMN1; SMN2MAPK1KMT2ATP53HTT | |
| SCHEMBL9156433 | 0.85 | MAPT (0.46) | GAASMN1; SMN2MCHR1MAPK1KMT2A | |
| SCHEMBL27488424 | 0.85 | KMT2A (0.37) | SMN1; SMN2MAPK1KMT2ATP53HTT | |
| SCHEMBL8033743 | 0.85 | MAPK1 (0.46) | SMN1; SMN2MAPK1KMT2ATP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |