Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033942 | 0.90 | KMT2A (0.40) | SMN1; SMN2MAPTLMNAKMT2AALDH1A1 | |
| SCHEMBL8020564 | 0.89 | KDM4E (0.37) | SMN1; SMN2GAAKDM4EMAPTKMT2A | |
| SCHEMBL8036207 | 0.88 | GRM5 (0.38) | SMN1; SMN2GAAMAPTLMNAKMT2A | |
| SCHEMBL8029983 | 0.88 | SMN1; SMN2 (0.36) | SMN1; SMN2GAAKDM4EKMT2AALDH1A1 | |
| SCHEMBL8020589 | 0.87 | SMN1; SMN2 (0.35) | SMN1; SMN2GAAKDM4EBDKRB2KMT2A | |
| SCHEMBL8030465 | 0.86 | KMT2A (0.38) | SMN1; SMN2GAAKDM4EMAPTBDKRB2 | |
| SCHEMBL8036090 | 0.86 | GAA (0.41) | SMN1; SMN2GAAKDM4EMAPTTDP1 | |
| SCHEMBL8020628 | 0.86 | KMT2A (0.42) | SMN1; SMN2KDM4ELMNAKMT2AALDH1A1 | |
| SCHEMBL8031924 | 0.86 | KMT2A (0.35) | SMN1; SMN2GAAKDM4EBDKRB2KMT2A | |
| SCHEMBL8030755 | 0.85 | KMT2A (0.47) | SMN1; SMN2GAAMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |