Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.70 |
| ▸ | HRH1 | P35367 | 16/20 | 0.70 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.60 |
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | HTR2C | P28335 | 3/20 | 0.60 |
| ▸ | HTR7 | P34969 | 3/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 2/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | HTR1D | P28221 | 1/20 | 0.50 |
| ▸ | HTR1E | P28566 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HTR5A | P47898 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041282 | 0.93 | HTR6 (0.81) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL8032473 | 0.89 | HTR6 (0.88) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL8031143 | 0.83 | HTR6 (1.00) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL3627160 | 0.83 | HTR6 (0.86) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL8036730 | 0.83 | HTR6 (0.80) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL8044408 | 0.81 | HTR6 (0.67) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL8040987 | 0.79 | HTR6 (0.88) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL8035383 | 0.78 | HRH1 (0.70) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL8034682 | 0.78 | HTR6 (0.88) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL8036725 | 0.77 | HTR6 (0.72) | HTR6HRH1ADRA2AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082268-A2 | LIGANDS OF α-ADRENOCEPTORS AND OF DOPAMINE, HISTAMINE, IMIDAZOLINE AND SEROTONIN RECEPTORS AND THE USE THEREOF | ALLA CHEM, LLC (US) | 2009-07-02 | — | — | WO | disclosed |