Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL7800261 | 0.97 | KDM4E (0.48) | KDM4EPOLBMAPK1ALDH1A1MAPT | |
| Ornithine Aketoglutarate SCHEMBL7792959 | 0.93 | KDM4E (0.44) | KDM4EPOLBMAPK1ALDH1A1MAPT | |
| Ornithine SCHEMBL7792961 | 0.93 | KDM4E (0.44) | KDM4EPOLBMAPK1ALDH1A1MAPT | |
| Ornithine SCHEMBL7801486 | 0.91 | KDM4E (0.42) | KDM4EPOLBMAPK1ALDH1A1MAPT | |
| Ornithine Aketoglutarate SCHEMBL7801491 | 0.91 | KDM4E (0.42) | KDM4EPOLBMAPK1ALDH1A1MAPT | |
| Lysine SCHEMBL7801523 | 0.91 | LTA4H (0.45) | KDM4EPOLBMAPK1ALDH1A1MAPT | |
| Lysine SCHEMBL7801526 | 0.91 | LTA4H (0.45) | KDM4EPOLBMAPK1ALDH1A1MAPT | |
| Phenylacetic Acid SCHEMBL7798038 | 0.89 | LTA4H (0.42) | KDM4EPOLBMAPK1ALDH1A1MAPT | |
| Phenylacetic Acid SCHEMBL7792817 | 0.89 | LTA4H (0.42) | KDM4EPOLBMAPK1ALDH1A1MAPT | |
| Ornithine SCHEMBL7801571 | 0.89 | KDM4E (0.46) | KDM4EPOLBALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |