SCHEMBL80374

SCHEMBL80374

CC(C)(C)NSc1nc2ccccc2s1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.58
HSD17B10 Q99714 4/20 0.58
FBP1 P09467 3/20 0.58
HPGD P15428 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
ADRA2A P08913 1/20 0.58
ADORA3 P0DMS8 1/20 0.58
DRD2 P14416 1/20 0.58
ALOX15 P16050 1/20 0.58
ADRA2B P18089 1/20 0.58
ADRA2C P18825 1/20 0.58
DRD1 P21728 1/20 0.58
MC5R P33032 1/20 0.58
OPRM1 P35372 1/20 0.58
DRD3 P35462 1/20 0.58
OPRK1 P41145 1/20 0.58
CCR2 P41597 1/20 0.58
HTR6 P50406 1/20 0.58
SLC6A3 Q01959 1/20 0.58
PDK1 Q15118 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370541 1.00 ALDH1A1 (0.58) ALDH1A1HSD17B10FBP1HPGDTDP1
SCHEMBL6372950 0.98 ALDH1A1 (0.56) ALDH1A1HSD17B10FBP1HPGDTDP1
SCHEMBL30017383 0.98 ALDH1A1 (0.56) ALDH1A1HSD17B10FBP1HPGDTDP1
Tert-Butylamine SCHEMBL11814397 0.97 ALDH1A1 (0.54) ALDH1A1HSD17B10FBP1HPGDTDP1
2-Mercaptobenzothiazole SCHEMBL28150676 0.91 ALDH1A1 (0.49) ALDH1A1HSD17B10FBP1HPGDTDP1
SCHEMBL8896302 0.90 ALDH1A1 (0.48) ALDH1A1HSD17B10FBP1HPGDTDP1
SCHEMBL6912219 0.87 ALDH1A1 (0.44) ALDH1A1HSD17B10FBP1HPGDTDP1
SCHEMBL443416 0.85 ALDH1A1 (0.54) ALDH1A1HSD17B10FBP1HPGDTDP1
SCHEMBL8511864 0.84 ALDH1A1 (0.51) ALDH1A1HSD17B10FBP1HPGDTDP1
SCHEMBL5677006 0.84 LMNA (0.55) ALDH1A1HSD17B10FBP1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14622 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748879-A1 ANTIOXIDANT COMPOSITION HAVING GOOD OZONE AGING RESISTANCE, AND RUBBER COMPOSITION AND USE THEREOF Sennics Co., Ltd. (CN) 2026-05-27 EP claimed
EP-4748880-A1 FATIGUE- AND AGING-RESISTANT RUBBER COMPOSITION AND USE THEREOF Sennics Co., Ltd. (CN) 2026-05-27 EP claimed
EP-4748829-A1 ANTIOXIDANT RESISTANT TO DAMP-HEAT AGING AND OZONE AGING, AND RUBBER COMPOSITION AND USE THEREOF Sennics Co., Ltd. (CN) 2026-05-27 EP claimed
EP-4745189-A1 VULCANIZATION AID AND PREPARATION METHOD THEREFOR, RUBBER COMPOSITION, RUBBER PRODUCT AND TIRE Eve Rubber Institute Co., Ltd. (CN) 2026-05-20 EP claimed
CN-122060232-A High-durability self-repairing type tire composite material and preparation method thereof 青岛茂驰橡胶制品有限公司 2026-05-19 CN claimed
CN-120795417-B Application of waste diatomite white carbon black, sole material, preparation method and application thereof 上海唯革思生物科技有限公司 2026-05-19 CN claimed
CN-122037333-A Rubber in-mold foaming lightweight sports shoe material and preparation method thereof 鸿星尔克(商丘)实业有限公司 2026-05-15 CN claimed
CN-122037338-A Tread rubber composition based on bio-based lignin and mixing method thereof 中策橡胶集团股份有限公司 2026-05-15 CN claimed
CN-122037329-A Double-network crosslinked carcass rubber composition of cracked carbon black-bio-based liquid rubber and preparation method thereof 中策橡胶集团股份有限公司 2026-05-15 CN claimed
US-20260132099-A1 ANTIOXIDANT RESISTANT TO DAMP-HEAT AGING AND OZONE AGING, AND RUBBER COMPOSITION AND USE THEREOF SENNICS CO., LTD. (CN) 2026-05-14 US claimed
EP-0169382-A2 Process for pelletization of powder materials and products therefrom The B.F. GOODRICH Company (US) 1986-01-29 EP claimed
US-4463120-A Process for preparing an aqueous adhesive composition SWS SILICONES CORPORATION (US) 1984-07-31 US claimed
US-4430466-A Benzothiazyl sulfenamides as scorch retardants for mercaptosilane-coupled silica filled-rubber compounds PHILLIPS PETROLEUM COMPANY (US) 1984-02-07 US claimed
US-4339506-A A THIURAM Martin, Chloeta F. (US) 1982-07-13 US claimed
US-4098858-A DUSTLESS FREE FLOWING RUBBER ADDITIVES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-07-04 US claimed
US-4012332-A BENZOTHIAZOLE SULFENAMIDE, A THIURAM SULFIDE OR METAL DITHIOCARBAMATE, COPPER 2-MERCAPTOBENZOTHIAZOLE AMERICAN CYANAMID COMPANY (US) 1977-03-15 US claimed
US-4002594-A THIOMORPHOLINE PPG INDUSTRIES, INC. (US) 1977-01-11 US claimed
US-3969350-A Base catalysis of azolesulfenamides and sulfur to aminodithioazoles MONSANTO COMPANY (US) 1976-07-13 US claimed
US-3965077-A VULCANIZATION RETARDERS THE B. F. GOODRICH COMPANY (US) 1976-06-22 US claimed
US-3931090-A POLYISOPRENE, METAL OXIDE, ANTIOXIDANT, CURING XEROX CORPORATION (US) 1976-01-06 US claimed