Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8023297 | 0.91 | PTGS2 (0.73) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL8037374 | 0.87 | PTGS2 (0.56) | PTGS2PTGS1ABCB11ALDH1A1 | |
| SCHEMBL8033503 | 0.86 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL8033128 | 0.86 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL8033502 | 0.86 | PTGS2 (0.75) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL8023471 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8037362 | 0.84 | PTGS2 (0.66) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL8032927 | 0.82 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL8032936 | 0.81 | PTGS2 (0.60) | PTGS2PTGS1CA1CA2CA9 | |
| SCHEMBL7463018 | 0.81 | PTGS2 (0.81) | PTGS2PTGS1ABCB11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000066562-A1 | PYRAZOLES HAVING ANTIINFLAMMATORY ACTIVITY | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-09 | — | — | WO | claimed |
| WO-2000066562-A1 | PYRAZOLES HAVING ANTIINFLAMMATORY ACTIVITY | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-09 | — | — | WO | disclosed |