Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.75 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | RPA1 | P27694 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032930 | 0.91 | PTGS2 (0.75) | PTGS2CA1CA2CA9CHRNA7 | |
| SCHEMBL8022815 | 0.89 | PTGS2 (0.60) | PTGS2ALOX5 | |
| SCHEMBL8037455 | 0.86 | PTGS2 (0.73) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL8023471 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8039677 | 0.83 | PTGS2 (0.66) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL8037140 | 0.80 | PTGS2 (0.61) | PTGS2CA1CA2CA9 | |
| SCHEMBL8037107 | 0.79 | PTGS2 (0.76) | PTGS2CA1CA2CA9 | |
| SCHEMBL8023934 | 0.78 | PTGS2 (0.73) | PTGS2CA1CA2CA9CHRNA7 | |
| SCHEMBL8039648 | 0.78 | PTGS2 (0.58) | PTGS2CA1CA2CA9PTGS1 | |
| SCHEMBL8033030 | 0.78 | PTGS2 (0.72) | PTGS2CA1CA2CA9CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000066562-A1 | PYRAZOLES HAVING ANTIINFLAMMATORY ACTIVITY | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-09 | — | — | WO | disclosed |