Anisaldehyde

Anisaldehyde

SCHEMBL8037525

COc1ccc(C=O)cc1.NCC(N)C(=O)O

nearest known ligand 0.58

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Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.58
CYP2A6 P11509 1/20 0.58
GRIK1 P39086 2/20 0.54
GRIK2 Q13002 2/20 0.54
KIF11 P52732 3/20 0.47
LDHA P00338 1/20 0.45
THRB P10828 1/20 0.45
ATM Q13315 1/20 0.45
GRM8 O00222 1/20 0.45
GRM6 O15303 1/20 0.45
GRM4 Q14833 1/20 0.45
GSK3B P49841 1/20 0.44
SLC1A5 Q15758 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
F3 P13726 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
ALDH1A3 P47895 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anisaldehyde SCHEMBL8037521 1.00 ALDH1A1 (0.58) ALDH1A1CYP2A6GRIK1GRIK2KIF11
Anisaldehyde SCHEMBL27955060 0.87 ALDH1A1 (0.56) ALDH1A1CYP2A6GRIK1GRIK2KIF11
Anisaldehyde SCHEMBL27955059 0.87 ALDH1A1 (0.56) ALDH1A1CYP2A6GRIK1GRIK2KIF11
Anisaldehyde SCHEMBL7617228 0.85 GSR (0.53) ALDH1A1CYP2A6GRIK1GRIK2KIF11
Anisaldehyde SCHEMBL7617225 0.85 GSR (0.53) ALDH1A1CYP2A6GRIK1GRIK2KIF11
Diaminopropanoic Acid SCHEMBL8035556 0.84 GRIK1 (0.59) ALDH1A1GRIK1GRIK2SLC1A5NPC1
Diaminopropanoic Acid SCHEMBL8035562 0.84 GRIK1 (0.59) ALDH1A1GRIK1GRIK2SLC1A5NPC1
Diaminopropanoic Acid SCHEMBL8039131 0.83 CYP2A6 (0.53) ALDH1A1CYP2A6GRIK1GRIK2KIF11
Diaminopropanoic Acid SCHEMBL8039134 0.83 CYP2A6 (0.53) ALDH1A1CYP2A6GRIK1GRIK2KIF11
Anisaldehyde SCHEMBL7798026 0.82 ALDH1A1 (0.68) ALDH1A1CYP2A6THRBATMGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127381-A A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY LION BIOSCIENCE AG (DE) 2000-10-03 US disclosed