Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.59 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | FOS | P01100 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diaminopropanoic Acid SCHEMBL8035556 | 1.00 | GRIK1 (0.59) | GRIK1GRIK2NPC1RAB9ATDP1 | |
| Lysine SCHEMBL8039215 | 0.86 | GRIK1 (0.54) | GRIK1GRIK2NPC1RAB9ATDP1 | |
| Lysine SCHEMBL8039212 | 0.86 | GRIK1 (0.54) | GRIK1GRIK2NPC1RAB9ATDP1 | |
| Glycine SCHEMBL7801464 | 0.85 | NPC1 (0.55) | GRIK1GRIK2NPC1RAB9ATDP1 | |
| Anisaldehyde SCHEMBL8037521 | 0.84 | ALDH1A1 (0.58) | GRIK1GRIK2NPC1RAB9AALDH1A1 | |
| Anisaldehyde SCHEMBL8037525 | 0.84 | ALDH1A1 (0.58) | GRIK1GRIK2NPC1RAB9AALDH1A1 | |
| Cyclohexylamine SCHEMBL8041423 | 0.82 | GRIK1 (0.43) | GRIK1GRIK2NPC1RAB9ATDP1 | |
| 2-(Aminomethyl)Phenol SCHEMBL8025682 | 0.82 | SLC1A5 (0.45) | GRIK1GRIK2NPC1RAB9ATDP1 | |
| Cyclohexylamine SCHEMBL8041427 | 0.82 | GRIK1 (0.43) | GRIK1GRIK2NPC1RAB9ATDP1 | |
| 2-(Aminomethyl)Phenol SCHEMBL8025681 | 0.82 | SLC1A5 (0.45) | GRIK1GRIK2NPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |