Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 9/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803702 | 0.86 | PRKCA (0.36) | PRKCAMMP12NR1I2 | |
| SCHEMBL792596 | 0.85 | PRKCA (0.34) | TNIKPTGER2PRKCAMMP12NR1I2 | |
| SCHEMBL12510208 | 0.84 | PRKCA (0.34) | PRKCAMMP12NR1I2 | |
| SCHEMBL774184 | 0.83 | NR1I2 (0.40) | PRKCAMMP12NR1I2KCNH2 | |
| SCHEMBL14572895 | 0.82 | NPC1 (0.35) | TNIKPRKCAMMP12NR1I2KCNH2 | |
| SCHEMBL804237 | 0.81 | PRKCA (0.46) | PRKCAMMP12NR1I2KCNH2 | |
| SCHEMBL792592 | 0.81 | KCNH2 (0.33) | TNIKHCRTR1PRKCAMMP12NR1I2 | |
| SCHEMBL10283558 | 0.81 | PRKCA (0.34) | PRKCAMMP12NR1I2ALDH1A1 | |
| SCHEMBL803906 | 0.81 | PRKCA (0.44) | PRKCAMMP12NR1I2 | |
| Hydrochloric Acid SCHEMBL771873 | 0.81 | PRKCA (0.46) | PRKCAMMP12NR1I2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC. (JP) | 2012-03-22 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070409-A1 | TETRACYCLIC FUSED HETEROCYCLIC COMPOUND AND USE THEREOF AS HCV POLYMERASE INHIBITOR | POLI, TERT, ZC3HAV1 | TNIK 2346/4885PTGER2 4650/4885HCRTR1 4616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.