SCHEMBL8037705

SCHEMBL8037705

CC1(C)C(C=O)C1OC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10659098 0.81
SCHEMBL3251068 0.79
SCHEMBL10828119 0.78 HPGD (0.31)
SCHEMBL9928650 0.78
SCHEMBL3254461 0.78
SCHEMBL2967436 0.78 ALOX15 (0.41)
SCHEMBL3629629 0.78
SCHEMBL10828326 0.78 HPGD (0.31)
SCHEMBL10828172 0.78 LMNA (0.30)
SCHEMBL3252747 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274314-B1 PROCESS FOR THE PREPARATION OF PENTAFLUOROPHENYLMETHYL 2,2-DIMETHYL-3-FORMYLCYCLOPROPANECARBOXYLATE, AND ITS USE IN THE SYNTHESIS OF PESTICIDAL PRODUCTS ROUSSEL-UCLAF (FR) 1990-11-07 EP claimed
EP-0842137-B1 A PROCESS FOR THE PREPARATION OF CYCLOPROPANE CARBOXYLIC ACIDS AND INTERMEDIATES THEREFOR CHEMINOVA AGRO AS (DK) 2000-04-05 EP disclosed
US-5986130-A REACTION OF HYDROXYTETRAHYDROFURANONE AND HALOFLUORINATED ETHANE IN THE PRESENCE OF ZINC CHEMINOVA AGRO A/S (DK) 1999-11-16 US disclosed
US-5278322-A Process ROUSSEL UCLAF (FR) 1994-01-11 US disclosed
US-5089511-A Trifluoromethylvinyl compounds ROUSSEL UCLAF (FR) 1992-02-18 US disclosed
US-5004822-A Isomers of 3-acetyl-2,2-dimethyl cyclopropane carboxylic acid derivatives NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1991-04-02 US disclosed
US-4920231-A Reacting with trifluoroacetic acid with halovinyl compound in presence of cuprous salt ROUSSEL UCLAF (FR) 1990-04-24 US disclosed
US-4879302-A Certain oximino-cyclopropane carboxylates having insecticidal activity ROUSSEL VCLAF (FR) 1989-11-07 US disclosed
US-4622337-A INSECTICIDES NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1986-11-11 US disclosed
EP-0043143-B1 PROCESS FOR STEREOSELECTIVELY SYNTHETIZING CYCLOPROPANE CARBOXYLATES AS INTERMEDIATES FOR PYRETHROIDS Montedison S.p.A. (IT) 1985-06-19 EP disclosed
US-4485238-A Preparation of ((6-substituted phenoxy-2-pyridinyl)-methyl)-3-(2,2-bis(trifluoromethyl)-1-ethenyl)-2,2-dimethylcyclopropane carboxylates THE DOW CHEMICAL COMPANY (US) 1984-11-27 US disclosed
US-4464391-A Pesticides NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1984-08-07 US disclosed
US-4442301-A DEHYDROHALOGENATION, CYCLIZATION MONTEDISON S.P.A. (IT) 1984-04-10 US disclosed
US-4356187-A INSECTICIDES ROUSSEL UCLAF (FR) 1982-10-26 US disclosed
EP-0043143-A2 Process for stereoselectively synthetizing cyclopropane carboxylates as intermediates for pyrethroids Montedison S.p.A. (IT) 1982-01-06 EP disclosed