Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28341996 | 1.00 | MDM4 (0.49) | MDM4TP53CASP3KMT2APIN1 | |
| SCHEMBL1738680 | 1.00 | MDM4 (0.49) | MDM4TP53CASP3KMT2APIN1 | |
| SCHEMBL30785203 | 1.00 | MDM4 (0.49) | MDM4TP53CASP3KMT2APIN1 | |
| SCHEMBL3439365 | 0.93 | CASP3 (0.48) | MDM4TP53CASP3KMT2APIN1 | |
| SCHEMBL5500174 | 0.89 | MDM4 (0.44) | MDM4TP53CASP3KMT2APIN1 | |
| SCHEMBL119402 | 0.89 | CASP3 (0.50) | MDM4TP53CASP3KMT2APIN1 | |
| SCHEMBL1738651 | 0.89 | CASP3 (0.50) | MDM4TP53CASP3KMT2APIN1 | |
| SCHEMBL2366569 | 0.89 | CASP3 (0.50) | MDM4TP53CASP3KMT2APIN1 | |
| SCHEMBL2366563 | 0.89 | CASP3 (0.50) | MDM4TP53CASP3KMT2APIN1 | |
| SCHEMBL31575313 | 0.89 | CASP3 (0.50) | MDM4TP53CASP3KMT2APIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989136-A1 | PEPTIDES HAVING CYCLIC STRUCTURES AND EXERTING P53 PROTEIN ACTIVTY-RESTORING EFFECT ON P53 PROTEIN MUTANTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-03-29 | — | — | EP | disclosed |