SCHEMBL8037890

SCHEMBL8037890

CC(C)(C)OOCC(=CC(=O)O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
TSHR P16473 1/20 0.42
GRIK1 P39086 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4732193 1.00 KDM4E (0.42) KDM4ETSHRGRIK1
SCHEMBL9444022 0.84 GRIK1 (0.35) GRIK1
SCHEMBL8458415 0.81 KDM4E (0.39) KDM4ETSHR
SCHEMBL8931135 0.79 GRIK1 (0.41) GRIK1
SCHEMBL4732012 0.74 ALDH1A1 (0.30) TSHR
SCHEMBL9066247 0.73 TSHR (0.32) TSHR
SCHEMBL543679 0.72 TSHR (0.38) KDM4ETSHR
SCHEMBL8765345 0.69 TET2 (0.42) TSHRGRIK1
SCHEMBL9243879 0.69 TSHR (0.50) KDM4ETSHRGRIK1
SCHEMBL3628412 0.69 TSHR (0.50) KDM4ETSHRGRIK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3185011-A None JP disclosed
US-6127325-A GRAFT COPOLYMER OF AN OIL-SOLUBLE OLEFIN POLYMER AND OF A COPOLYMER (B) OF A MONOMER HAVING A PEROXIDE BOND WITH (METH)ACRYLATE; OR COPOLYMER (C) OF A PEROXIDE CONTAINING MONOMER AND SPECIFIED MONOMERS; NO PHASE SEPARATION NOF CORPORATION (JP) 2000-10-03 US disclosed
EP-0872539-A1 VISCOSITY INDEX IMPROVER, PROCESS FOR PREPARING THE SAME AND LUBRICATING OIL COMPOSITION NOF CORPORATION (JP) 1998-10-21 EP disclosed
JP-H03185011-A POLYMER TYPE POLYMERIZATION INITIATOR TOME SANGYO KK 1991-08-13 JP disclosed