SCHEMBL8458415

SCHEMBL8458415

CC(C)(C)OOCCC(=CC(=O)O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4732193 0.81 KDM4E (0.42) KDM4ETSHR
SCHEMBL8037890 0.81 KDM4E (0.42) KDM4ETSHR
SCHEMBL19118007 0.74 ALDH1A1 (0.37) TSHR
SCHEMBL10386720 0.72 TSHR (0.43) KDM4ETSHR
SCHEMBL9008292 0.72 TSHR (0.43) KDM4ETSHR
SCHEMBL9240792 0.71 KDM4E (0.46) KDM4ETSHR
SCHEMBL28488698 0.71 TSHR (0.62) KDM4ETSHR
SCHEMBL9444022 0.69 GRIK1 (0.35)
SCHEMBL16247178 0.69 KDM4E (0.41) KDM4ETSHR
SCHEMBL16247179 0.69 KDM4E (0.41) KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0785964-B1 NON-LINEAR STYRENIC POLYMER-BASED FOAMS DOW CHEMICAL CO (US) 1999-04-14 EP disclosed