Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.47 |
| ▸ | RARA | P10276 | 2/20 | 0.47 |
| ▸ | RARG | P13631 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14526059 | 0.90 | GCGR (0.45) | RARBRARARARGHTR2AHSD17B10 | |
| SCHEMBL7920156 | 0.89 | MEN1 (0.43) | RARBRARARARGALDH1A1LMNA | |
| SCHEMBL7928543 | 0.83 | DHODH (0.38) | RARBRARARARGHSD17B10ALDH1A1 | |
| SCHEMBL5722722 | 0.82 | PTGS2 (0.50) | RARBRARARARGHSD17B10TSHR | |
| SCHEMBL7557837 | 0.82 | RARB (0.45) | RARBRARARARGHTR2AHSD17B10 | |
| SCHEMBL7926802 | 0.81 | PTGS2 (0.46) | RARBRARARARGHTR2AHSD17B10 | |
| SCHEMBL13002918 | 0.80 | RARB (0.33) | RARBRARARARGTSHRTP53 | |
| SCHEMBL5722885 | 0.79 | MEN1 (0.43) | RARBRARARARGALDH1A1LMNA | |
| SCHEMBL3167793 | 0.79 | RARB (0.41) | RARBRARARARGDHODH | |
| SCHEMBL6059923 | 0.79 | RARB (0.41) | RARBRARARARGDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159561-A | FOR FERROELECTRIC SWITCHING AND/OR DISPLAY DEVICES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |
| EP-0946474-A1 | 1,3-DIFLUORONAPTHALENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027037-A1 | 1,3-DIFLUORONAPTHALENE DERIVATIVES FOR LIQUID CRYSTAL MIXTURES | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |