Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039708 | 1.00 | PTPN1 (0.40) | PTPN1MAOBSTAT3PTGESALOX5 | |
| SCHEMBL6405116 | 1.00 | PTPN1 (0.40) | PTPN1MAOBSTAT3PTGESALOX5 | |
| SCHEMBL8039546 | 1.00 | PTPN1 (0.40) | PTPN1MAOBSTAT3PTGESALOX5 | |
| SCHEMBL8039689 | 0.99 | PTPN1 (0.38) | PTPN1MAOBSTAT3PTGESALOX5 | |
| SCHEMBL8041172 | 0.90 | TSPO (0.40) | PTPN1MAOBSTAT3ABCC1 | |
| SCHEMBL6406664 | 0.89 | TSPO (0.39) | ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL8037926 | 0.89 | TSPO (0.39) | ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL8038293 | 0.89 | TSPO (0.39) | ALDH1A1LMNAKMT2ATSHR | |
| SCHEMBL8037891 | 0.88 | TSPO (0.40) | ALDH1A1LMNAPARP10KMT2ATSHR | |
| SCHEMBL8027781 | 0.86 | ABCC1 (0.40) | MAOBSTAT3PTGESALOX5EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |