Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6406664 | 1.00 | TSPO (0.39) | TSPOPDE5AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8037926 | 1.00 | TSPO (0.39) | TSPOPDE5AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8037891 | 0.99 | TSPO (0.40) | TSPOPDE5AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8037916 | 0.91 | TSPO (0.44) | TSPOPDE5AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8039708 | 0.89 | PTPN1 (0.40) | ALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL8039546 | 0.89 | PTPN1 (0.40) | ALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL6405116 | 0.89 | PTPN1 (0.40) | ALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL8038304 | 0.89 | PTPN1 (0.40) | ALDH1A1KMT2ATSHRLMNA | |
| SCHEMBL8039689 | 0.88 | PTPN1 (0.38) | KMT2ATSHRACACBPOLBLMNA | |
| SCHEMBL8037976 | 0.87 | MMP13 (0.36) | KDM4EALDH1A1ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |