Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032664 | 0.89 | CNR2 (0.42) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL8031508 | 0.86 | ATM (0.46) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL8040669 | 0.86 | NPSR1 (0.42) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL8024878 | 0.85 | NAMPT (0.40) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL8041741 | 0.85 | NPSR1 (0.42) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL8040303 | 0.85 | NPSR1 (0.42) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL8023419 | 0.84 | NPSR1 (0.39) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL8037630 | 0.83 | NAMPT (0.40) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL8039494 | 0.81 | VCP (0.39) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL8038516 | 0.81 | NPSR1 (0.39) | SMN1; SMN2NPC1RAB9ANPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |