Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | PDE5A | O76074 | 2/20 | 0.36 |
| ▸ | ACP1 | P24666 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037126 | 0.90 | PLA2G1B (0.41) | NPSR1TSHRHPGDPLA2G1BATG4B | |
| SCHEMBL8040669 | 0.85 | NPSR1 (0.42) | NPSR1TSHRHPGDADORA3KDM4E | |
| SCHEMBL8039494 | 0.84 | VCP (0.39) | NPSR1TSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL8040303 | 0.82 | NPSR1 (0.42) | NPSR1TSHRHPGDKDM4EALDH1A1 | |
| SCHEMBL8041741 | 0.82 | NPSR1 (0.42) | NPSR1TSHRHPGDADORA3KDM4E | |
| SCHEMBL8038367 | 0.81 | SMN1; SMN2 (0.40) | NPSR1TSHRHPGDADORA3KDM4E | |
| SCHEMBL8034844 | 0.80 | CASP3 (0.46) | NPSR1TSHRPLA2G1BATG4BADORA3 | |
| SCHEMBL8032664 | 0.80 | CNR2 (0.42) | NPSR1TSHRHPGDADORA3KDM4E | |
| SCHEMBL8034467 | 0.78 | CNR1 (0.44) | SLC6A3CNR1NAMPT | |
| SCHEMBL8043493 | 0.77 | PLA2G1B (0.45) | NPSR1PLA2G1BATG4BADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080242-A1 | SUBSTITUTED 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |