Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 5/20 | 0.59 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.59 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30660479 | 0.84 | IMPDH2 (0.51) | AOC1AOC3IMPDH2LOXL2GAA | |
| SCHEMBL13731612 | 0.81 | IMPDH2 (0.43) | AOC1AOC3IMPDH2LOXL2ALDH1A1 | |
| SCHEMBL16702897 | 0.80 | AOC1 (0.59) | AOC1AOC3IMPDH2LOXL2GAA | |
| SCHEMBL11614582 | 0.78 | AOC1 (0.52) | AOC1AOC3IMPDH2LOXL2CA12 | |
| SCHEMBL28179929 | 0.77 | — | — | |
| SCHEMBL370783 | 0.76 | IMPDH2 (0.40) | AOC1AOC3IMPDH2LOXL2ALDH1A1 | |
| SCHEMBL5748797 | 0.74 | — | — | |
| SCHEMBL30210557 | 0.74 | — | — | |
| SCHEMBL3819598 | 0.74 | — | — | |
| SCHEMBL12833330 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0682655-B1 | METHOD FOR PREPARING 3-AMINO-2-CHLORO-4-ALKYLPYRIDINE OR -4-CYCLOALKYLPYRIDINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-05-03 | — | — | EP | claimed |
| US-5686618-A | Method for preparing 3-amino-2-chloro-4-alkylpyridine or-4-arylpyridine | BOEHRINGER INGELHEIM KG (DE) | 1997-11-11 | — | — | US | claimed |
| US-5686618-A | Method for preparing 3-amino-2-chloro-4-alkylpyridine or-4-arylpyridine | BOEHRINGER INGELHEIM KG (DE) | 1997-11-11 | — | — | US | disclosed |