SCHEMBL8038468

SCHEMBL8038468

Oc1nc(-c2ccccc2)nc(-c2ccccc2)n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.58
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
NTSR1 P30989 1/20 0.54
ADORA2A P29274 3/20 0.52
ADORA1 P30542 3/20 0.52
ADORA3 P0DMS8 2/20 0.52
ADORA2B P29275 2/20 0.52
POLB P06746 2/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
MAPK1 P28482 1/20 0.50
MAPT P10636 2/20 0.48
ALDH1A1 P00352 1/20 0.48
HPGD P15428 1/20 0.48
HTT P42858 1/20 0.46
NR1H4 Q96RI1 1/20 0.43
CHUK O15111 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22207818 0.95 MEN1 (0.55) L3MBTL1MEN1KMT2ANTSR1ADORA2A
SCHEMBL1534218 0.95 MEN1 (0.54) L3MBTL1MEN1KMT2ANTSR1ADORA2A
SCHEMBL29973391 0.90 MEN1 (0.55) L3MBTL1MEN1KMT2ANTSR1ADORA2A
SCHEMBL371042 0.86 L3MBTL1 (0.74) L3MBTL1MEN1KMT2ANTSR1ADORA2A
SCHEMBL17118709 0.84 L3MBTL1 (0.72) L3MBTL1MEN1KMT2ANTSR1ADORA2A
SCHEMBL3424182 0.84 ADORA2A (0.72) L3MBTL1MEN1KMT2ANTSR1ADORA2A
SCHEMBL19980484 0.84 KMO (0.48) L3MBTL1MEN1KMT2ANTSR1MAPT
SCHEMBL32688389 0.84 MEN1 (0.46) L3MBTL1MEN1KMT2ANTSR1ADORA2A
SCHEMBL18212420 0.83 L3MBTL1 (0.70) L3MBTL1MEN1KMT2ANTSR1ADORA2A
SCHEMBL75848 0.83 L3MBTL1 (0.70) L3MBTL1MEN1KMT2ANTSR1ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0497734-B1 Process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines CIBA SC HOLDING AG (CH) 2000-05-10 EP claimed
EP-0497734-A1 Process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines CIBA-GEIGY AG (CH) 1992-08-05 EP claimed
CN-118255725-A Preparation method of triazine compound 上海朗亿功能材料有限公司 2024-06-28 CN disclosed
CN-116143715-B Synthesis method of 2- (4, 6-diphenyl-1, 3, 5-triazin-2-yl) -5-n-hexyloxyphenol 江苏极易新材料有限公司 2023-11-24 CN disclosed
CN-116143715-A Synthesis method of 2- (4, 6-diphenyl-1, 3, 5-triazin-2-yl) -5-n-hexyloxyphenol 江苏极易新材料有限公司 2023-05-23 CN disclosed
CN-116120249-A Novel method for synthesizing s-triazine compound 中昊(大连)化工研究设计院有限公司 2023-05-16 CN disclosed
CN-116023343-A Preparation method of ultraviolet absorber UV-1577 intermediate 山东浩华新材料科技有限公司 2023-04-28 CN disclosed
EP-3908576-A1 A PROCESS FOR THE PREPARATION OF UV ABSORBERS BASF SE (DE) 2021-11-17 EP disclosed
EP-3160954-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-09-23 EP disclosed
WO-2020144094-A1 A PROCESS FOR THE PREPARATION OF UV ABSORBERS BASF SE (DE) 2020-07-16 WO disclosed
WO-2020144094-A1 A PROCESS FOR THE PREPARATION OF UV ABSORBERS BASF SE (DE) 2020-07-16 WO disclosed
EP-0497734-B1 Process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines CIBA SC HOLDING AG (CH) 2000-05-10 EP disclosed
JP-2000044550-A PRODUCTION OF 2-HYDROXY-4,6-DIARYL-S-TRIAZINE ASAHI DENKA KOGYO KK 2000-02-15 JP disclosed
EP-0556156-B1 Process for the preparation of 2-hydroxy-4,6-diaryl-1,3,5-triazine CIBA GEIGY AG (CH) 1996-09-25 EP disclosed
US-5288868-A Intermediates in synthesis of ultraviolet light absorbers CIBA-GEIGY CORPORATION (US) 1994-02-22 US disclosed
US-5288867-A Process for the preparation of 2-hydroxy-4,6-diaryl-1,3,5-triazines CIBA-GEIGY CORPORATION (US) 1994-02-22 US disclosed
EP-0556156-A1 Process for the preparation of 2-hydroxy-4,6-diaryl-1,3,5-triazine CIBA-GEIGY AG (CH) 1993-08-18 EP disclosed
EP-0555180-A1 Process for the preparation of 2-hydroxy-4,6-diazyl-1,3,5-triazines CIBA-GEIGY AG (CH) 1993-08-11 EP disclosed
US-5182389-A PROCESS FOR THE PREPARATION OF 2-(2',4'-DIHYDROXYPHENYL)-4,6-DIARYL-S-TRIAZINES CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
EP-0497734-A1 Process for the preparation of 2-(2',4'-dihydroxyphenyl)-4,6-diaryl-s-triazines CIBA-GEIGY AG (CH) 1992-08-05 EP disclosed