Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.64 |
| ▸ | BRD4 | O60885 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032078 | 0.88 | PPARG (0.62) | PPARGBRD4MEN1TP53PABPC1 | |
| SCHEMBL16713345 | 0.85 | PKM (0.54) | PPARGMEN1TP53PABPC1KMT2A | |
| SCHEMBL2314932 | 0.84 | SCD (0.66) | PPARGHDAC6SCD | |
| SCHEMBL22533960 | 0.82 | MEN1 (0.49) | PPARGMEN1TP53PABPC1KMT2A | |
| SCHEMBL28720229 | 0.82 | HCAR3 (0.49) | PPARGMEN1TP53PABPC1KMT2A | |
| SCHEMBL29424692 | 0.82 | HCAR3 (0.49) | PPARGMEN1TP53PABPC1KMT2A | |
| SCHEMBL2316656 | 0.82 | SCD (0.66) | SCD | |
| SCHEMBL8038702 | 0.78 | PPARG (0.65) | PPARGNR1I2HCAR3FGFR1 | |
| SCHEMBL13508660 | 0.78 | CYP11B1 (0.57) | PPARGBRD4MEN1TP53PABPC1 | |
| SCHEMBL1608124 | 0.77 | HDAC6 (0.63) | PPARGBRD4HDAC1HDAC6SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |