Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 10/20 | 0.46 |
| ▸ | CA2 | P00918 | 10/20 | 0.46 |
| ▸ | CA9 | Q16790 | 10/20 | 0.46 |
| ▸ | CA12 | O43570 | 9/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10604737 | 0.97 | POLB (0.59) | POLBLMNAKMT2AALDH1A1CYP2D6 | |
| SCHEMBL10604734 | 0.97 | POLB (0.59) | POLBLMNAKMT2AALDH1A1CYP2D6 | |
| SCHEMBL10526349 | 0.92 | POLB (0.53) | POLBLMNAKMT2AALDH1A1CYP2D6 | |
| SCHEMBL8038807 | 0.92 | POLB (0.60) | POLBLMNAKMT2AALDH1A1CYP2D6 | |
| SCHEMBL25913950 | 0.90 | LMNA (0.54) | POLBLMNAKMT2AALDH1A1CYP2D6 | |
| SCHEMBL10608406 | 0.90 | LMNA (0.57) | POLBLMNAKMT2AALDH1A1CYP2D6 | |
| SCHEMBL21097453 | 0.88 | POLB (0.79) | POLBLMNAKMT2AALDH1A1CYP2D6 | |
| SCHEMBL8931476 | 0.88 | POLB (0.79) | POLBLMNAKMT2AALDH1A1CYP2D6 | |
| SCHEMBL8931470 | 0.88 | POLB (0.79) | POLBLMNAKMT2AALDH1A1CYP2D6 | |
| SCHEMBL11176233 | 0.88 | POLB (0.55) | POLBLMNAKMT2AALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648279-B1 | ACCEPTOR FOR FUCOSYLTRANSFERASE | HEALTH RESEARCH INC (US) | 2000-03-15 | — | — | EP | disclosed |
| US-5620864-A | OLIGOSACCHARIDE CONTAINING SULFATE GROUP USED FOR DIAGNOSIS | HEALTH RESEARCH, INC. (US) | 1997-04-15 | — | — | US | disclosed |