Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11590192 | 0.82 | KDM4E (0.43) | KDM4ELMNAELANEESR1CHRM1 | |
| SCHEMBL11107828 | 0.82 | KDM4E (0.43) | KDM4ELMNAELANEESR1CHRM1 | |
| SCHEMBL8835026 | 0.82 | KDM4E (0.39) | KDM4ELMNAELANEESR1CHRM1 | |
| SCHEMBL8039606 | 0.79 | ELANE (0.32) | ELANEESR1 | |
| SCHEMBL8976102 | 0.79 | ELANE (0.32) | ELANEESR1 | |
| SCHEMBL9428729 | 0.77 | KDM4E (0.42) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL10390092 | 0.76 | ELANE (0.33) | KDM4ELMNAELANEESR1CHRM1 | |
| Ethyl Acetate SCHEMBL11262607 | 0.76 | KDM4E (0.39) | KDM4ELMNAELANEESR1CHRM1 | |
| SCHEMBL9318537 | 0.72 | KDM4E (0.33) | KDM4ELMNAELANEESR1CHRM1 | |
| SCHEMBL9317033 | 0.72 | PTGDR2 (0.34) | KDM4ELMNAELANEKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587436-B1 | Process for preparing carbapenem and penem compounds and new compounds involved in that process | SANKYO CO (JP) | 2000-05-10 | — | — | EP | disclosed |
| US-5614624-A | THIO SUBSTITUTED, ANTIBIOTICS, CHEMICAL INTERMEDIATES | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5541317-A | PENICILLIN DERIVATIVES, CYCLIZATION OF ESTERS OR THIOESTERS | SANKYO COMPANY, LIMITED (JP) | 1996-07-30 | — | — | US | disclosed |
| EP-0587436-A1 | Process for preparing carbapenem and penem compounds and new compounds involved in that process | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |