Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11107828 | 0.90 | KDM4E (0.43) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11590192 | 0.90 | KDM4E (0.43) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11115355 | 0.82 | ELANE (0.50) | ELANE | |
| SCHEMBL11109337 | 0.82 | ELANE (0.50) | ELANE | |
| SCHEMBL8038866 | 0.76 | KDM4E (0.32) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL11128916 | 0.75 | ELANE (0.41) | LMNAELANETSHR | |
| SCHEMBL9848082 | 0.70 | KDM4E (0.46) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9597108 | 0.70 | KDM4E (0.46) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| Ethyl Acetate SCHEMBL11279297 | 0.70 | ELANE (0.36) | ELANE | |
| SCHEMBL9598370 | 0.69 | KDM4E (0.47) | KDM4ELMNAESR1CHRM1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347181-A | Intermediates for producing bicyclic β-lactam-antibiotics | BEECHAM GROUP LIMITED (GB) | 1982-08-31 | — | — | US | disclosed |
| US-4289696-A | BETA-LACTAMASE INHIBITORY AGENTS WHICH ENHANCE ACTIVITY OF A PENICICILLIN OR CEPHALOSPORIN | BEECHAM GROUP LIMITED (GB) | 1981-09-15 | — | — | US | disclosed |
| US-4223038-A | THIENAMYCINS | BEECHAM GROUP LIMITED (GB) | 1980-09-16 | — | — | US | disclosed |