Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039606 | 1.00 | ELANE (0.32) | ELANEESR1PTGS1PDE4AABCC2 | |
| SCHEMBL9429357 | 0.86 | ELANE (0.35) | ELANEESR1PTGS1PDE4A | |
| SCHEMBL9427926 | 0.86 | — | — | |
| SCHEMBL8040731 | 0.83 | ELANE (0.32) | ELANE | |
| SCHEMBL8042493 | 0.83 | SMN1; SMN2 (0.31) | ELANE | |
| SCHEMBL8834929 | 0.83 | SMN1; SMN2 (0.31) | ELANE | |
| SCHEMBL9128902 | 0.82 | PTGS1 (0.42) | ELANEESR1PTGS1PDE4AABCC2 | |
| SCHEMBL8576696 | 0.82 | PTGS1 (0.42) | ELANEESR1PTGS1PDE4AABCC2 | |
| SCHEMBL9836778 | 0.82 | PTGS1 (0.42) | ELANEESR1PTGS1PDE4AABCC2 | |
| SCHEMBL8038866 | 0.79 | KDM4E (0.32) | ELANEESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541317-A | PENICILLIN DERIVATIVES, CYCLIZATION OF ESTERS OR THIOESTERS | SANKYO COMPANY, LIMITED (JP) | 1996-07-30 | — | — | US | disclosed |