Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16191445 | 0.85 | HTT (0.54) | HTTALDH1A1TAAR1EPHX2NPC1 | |
| SCHEMBL8040937 | 0.81 | MEN1 (0.39) | HTTALDH1A1EPHX2EPHX1KMT2A | |
| SCHEMBL8040010 | 0.81 | ALDH1A1 (0.42) | ALDH1A1TAAR1NPC1RAB9AEPHX1 | |
| SCHEMBL8042890 | 0.81 | HRH3 (0.45) | HTTALDH1A1TAAR1NPC1RAB9A | |
| SCHEMBL4564333 | 0.81 | HTT (0.50) | HTTALDH1A1TAAR1EPHX2NPC1 | |
| SCHEMBL8464214 | 0.81 | EPHX1 (0.47) | ALDH1A1TAAR1NPC1RAB9AEPHX1 | |
| SCHEMBL7209770 | 0.81 | HTT (0.47) | HTTALDH1A1TAAR1EPHX2NPC1 | |
| SCHEMBL28898677 | 0.81 | EPHX1 (0.36) | HTTALDH1A1EPHX2EPHX1 | |
| SCHEMBL3966885 | 0.80 | EPHX2 (0.44) | TAAR1EPHX2EPHX1TSHR | |
| SCHEMBL9390743 | 0.79 | ALDH1A1 (0.44) | HTTALDH1A1TAAR1EPHX2SLC18A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120238740-A1 | NON-POLAR AND POLAR LEAVING GROUPS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-09-20 | — | — | US | disclosed |
| EP-2454216-A1 | NON-POLAR AND POLAR LEAVING GROUPS | Bayer Pharma Aktiengesellschaft (DE) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011006610-A1 | NON-POLAR AND POLAR LEAVING GROUPS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238740-A1 | NON-POLAR AND POLAR LEAVING GROUPS | PGLS, RABGGTB, LNPEP | HTT 3991/4885ALDH1A1 2845/4885TAAR1 4432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.