Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of 3-Formylbenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UNG | P13051 | 2/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 3/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Formylbenzoic Acid SCHEMBL8039145 | 1.00 | UNG (0.48) | UNGGSRDPP7SRD5A1KMO | |
| Lysine SCHEMBL8039122 | 0.89 | GSR (0.48) | GSRDPP7 | |
| Lysine SCHEMBL8037277 | 0.88 | GSR (0.43) | GSRDPP7 | |
| Lysine SCHEMBL8037280 | 0.88 | GSR (0.43) | GSRDPP7 | |
| Lysine SCHEMBL8025620 | 0.88 | GSR (0.44) | GSRDPP7GRM4STSEPHX1 | |
| Lysine SCHEMBL8025623 | 0.88 | GSR (0.44) | GSRDPP7GRM4STSEPHX1 | |
| 3-Formylbenzoic Acid SCHEMBL8035774 | 0.88 | UNG (0.54) | UNGSRD5A1KMOGRM4STS | |
| 3-Formylbenzoic Acid SCHEMBL8035782 | 0.88 | UNG (0.54) | UNGSRD5A1KMOGRM4STS | |
| Lysine SCHEMBL8039357 | 0.88 | CTSB (0.42) | GSRDPP7 | |
| Lysine SCHEMBL8037742 | 0.88 | ALDH1A1 (0.42) | GSRDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |