Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16418313 | 1.00 | HDAC4 (0.33) | HDAC4BACE1AVPR1ANPY5R | |
| SCHEMBL2619824 | 1.00 | HDAC4 (0.33) | HDAC4BACE1AVPR1ANPY5R | |
| SCHEMBL2619829 | 0.85 | BACE1 (0.35) | BACE1 | |
| SCHEMBL12690003 | 0.85 | BACE1 (0.35) | BACE1 | |
| SCHEMBL12690280 | 0.85 | BACE1 (0.35) | BACE1 | |
| SCHEMBL13177584 | 0.85 | BACE1 (0.35) | BACE1 | |
| SCHEMBL12690286 | 0.80 | HDAC4 (0.39) | HDAC4 | |
| SCHEMBL2619978 | 0.79 | BACE1 (0.40) | BACE1 | |
| SCHEMBL7925283 | 0.79 | BACE1 (0.45) | BACE1 | |
| SCHEMBL3300585 | 0.79 | BACE1 (0.45) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091016-A1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-07-23 | — | — | WO | disclosed |