Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.62 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.62 |
| ▸ | XDH | P47989 | 5/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21402773 | 0.84 | FGFR1 (0.61) | FGFR1FGFR2XDHADORA2BADORA2A | |
| SCHEMBL1286943 | 0.77 | FGFR1 (1.00) | FGFR1FGFR2XDHADORA2BPNP | |
| SCHEMBL1286927 | 0.72 | FGFR1 (0.66) | FGFR1FGFR2XDHADORA2BADORA2A | |
| SCHEMBL3757546 | 0.71 | FGFR1 (0.59) | FGFR1FGFR2XDHADORA2BADORA2A | |
| SCHEMBL8039267 | 0.71 | FGFR1 (0.38) | FGFR1FGFR2XDHADORA2BPNP | |
| SCHEMBL7688477 | 0.68 | GRIA1 (0.75) | FGFR1FGFR2XDHADORA2BADORA2A | |
| SCHEMBL378879 | 0.67 | ADORA2B (1.00) | FGFR1FGFR2XDHADORA2BADORA2A | |
| SCHEMBL6889649 | 0.66 | ADORA2B (0.69) | XDHADORA2BADORA2AADORA3ADORA1 | |
| SCHEMBL14716577 | 0.65 | FGFR1 (0.56) | FGFR1FGFR2XDH | |
| SCHEMBL7058942 | 0.65 | ADORA2B (0.56) | FGFR1FGFR2XDHADORA2BADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051385-A | A NUCLEIC ACID SEQUENCES THAT ENCODES A PROTEIN B5T74 THAT CONFERS THE ABILITY OF HERPES SIMPLEX VIRUS TO INFECT AND REPLICATE IN NON-PERMISSIVE CELLS; SCREENING VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2000-04-18 | — | — | US | disclosed |
| WO-1999020761-A2 | COMPOSITIONS AND METHODS FOR IDENTIFYING AND TESTING THERAPEUTICS AGAINST HSV INFECTION | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1999-04-29 | — | — | WO | disclosed |