Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143128 | 0.74 | MTNR1A (0.47) | CYP2D6CYP1A2CYP2C19SIGMAR1TDP1 | |
| SCHEMBL3225216 | 0.72 | MTNR1A (0.45) | CYP2D6CYP1A2CYP2C19SIGMAR1TDP1 | |
| SCHEMBL11939041 | 0.72 | HTR1B (0.57) | CYP2D6CYP1A2CYP2C19LMNAHTT | |
| Hydrochloric Acid SCHEMBL29368932 | 0.71 | BCHE (0.52) | CYP2D6CYP1A2CYP2C19LMNAHTT | |
| SCHEMBL18243028 | 0.71 | CYP2C19 (0.44) | CYP2D6CYP1A2CYP2C19HTTHPGD | |
| SCHEMBL3244852 | 0.71 | MTNR1A (0.44) | CYP1A2CYP2C19SIGMAR1TDP1 | |
| SCHEMBL14148676 | 0.70 | LMNA (0.60) | CYP2D6CYP1A2CYP2C19LMNAHTT | |
| SCHEMBL3245817 | 0.70 | CYP2D6 (0.66) | CYP2D6CYP1A2CYP2C19LMNAHTT | |
| SCHEMBL143458 | 0.70 | MTNR1A (0.49) | CYP2D6CYP1A2CYP2C19ALDH1A1HPGD | |
| SCHEMBL27603918 | 0.70 | CYP2D6 (0.66) | CYP2D6CYP1A2CYP2C19LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |