SCHEMBL8039397

SCHEMBL8039397

Oc1c(-c2ccccc2)cccc1-c1ccccc1P(C1CCCCC1)C1CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.38
ALDH1A1 P00352 5/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
ROCK2 O75116 1/20 0.36
GAA P10253 1/20 0.35
PTPN5 P54829 3/20 0.35
PTPN2 P17706 1/20 0.35
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28152697 0.86 ROCK2 (0.38) HNF4AALDH1A1MEN1KMT2ANPSR1
SCHEMBL29353025 0.86 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL1159030 0.86 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL133189 0.86 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL1931350 0.84 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL5840557 0.84 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL33526641 0.84 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ANPSR1LMNA
Hydrochloric Acid SCHEMBL29639278 0.84 ALDH1A1 (0.40) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL16694717 0.84 GAA (0.39) ALDH1A1MEN1KMT2ANPSR1LMNA
SCHEMBL520084 0.82 BCHE (0.37) ALDH1A1MEN1KMT2ANPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000068237-A1 PD- AND NI COMPLEXES OF BIPHENYL-2-YL-PHOSPHANES AND THEIR USE IN CATALYTIC C,C-, C,N- AND C,O-COUPLINGS CLARIANT GMBH (DE) 2000-11-16 WO disclosed