Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11153547 | 0.83 | MEN1 (0.43) | MEN1KMT2AHTTNR3C2CA12 | |
| SCHEMBL8039424 | 0.79 | HTT (0.40) | MEN1KMT2AHTTNR3C2CA12 | |
| SCHEMBL27395569 | 0.79 | CDK1 (0.40) | MEN1KMT2AHTTNR3C2CA12 | |
| SCHEMBL8038722 | 0.78 | APOBEC3G (0.47) | KMT2ACA12CA9ALDH1A1PKM | |
| SCHEMBL8038717 | 0.74 | CA12 (0.60) | MEN1KMT2AHTTCA12CA9 | |
| SCHEMBL11381733 | 0.73 | MEN1 (0.34) | MEN1KMT2AHTTNR3C2CA12 | |
| SCHEMBL8052348 | 0.73 | MEN1 (0.36) | MEN1KMT2AHTTNR3C2CA12 | |
| SCHEMBL11379025 | 0.73 | MEN1 (0.36) | MEN1KMT2AHTTNR3C2CA12 | |
| SCHEMBL11384867 | 0.73 | MEN1 (0.34) | MEN1KMT2AHTTNR3C2CA12 | |
| SCHEMBL1705973 | 0.71 | NR3C2 (0.41) | MEN1KMT2AHTTNR3C2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756590-A | MIXING TERPOLYMER WITH HALOTHIOSULFONAMIDE AND INCLUDING A HYDROHALIC ACID ACCEPTOR; OZONE RESISTANT TIRE SIDEWALLS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-05-26 | — | — | US | claimed |
| EP-0312484-B1 | Modification process | GOODYEAR TIRE & RUBBER (US) | 1993-11-24 | — | — | EP | claimed |
| EP-0377552-B1 | PROCESS FOR SYNTHESIZING N-CHLOROTHIO-SULFONAMIDES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-07-28 | — | — | EP | claimed |
| US-5187240-A | Treatment of polyolefin polymer with N-halothiosulfonamide | EXXON CHEMICAL PATENTS INC. (US) | 1993-02-16 | — | — | US | claimed |
| US-5037896-A | Selective catalytic process for preparing N-halothiosulfonamide modified polyolefins | EXXON CHEMICAL PATENTS INC. (US) | 1991-08-06 | — | — | US | claimed |
| US-5034467-A | For polymers of high tensile strength | EXXON CHEMICAL PATENTS, INC. (US) | 1991-07-23 | — | — | US | claimed |
| US-5034468-A | For polymers of high tensile strength | EXXON CHEMICAL PATENTS INC. (US) | 1991-07-23 | — | — | US | claimed |
| US-4992583-A | Reacting n,n'-dithiobis (sulfonamide) with chlorine gas or sulfuryl chloride | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-02-12 | — | — | US | claimed |
| US-4956420-A | USING A COPPER, ANTIMONY, BISMITH OR TIN SALT OF AN ORGANIC MONO-OR POLYCARBOXYLIC ACID | EXXON CHEMICAL PATENTS INC. (US) | 1990-09-11 | — | — | US | claimed |
| EP-0377552-A1 | Process for synthesizing N-chlorothio-sulfonamides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-07-11 | — | — | EP | claimed |
| US-4910266-A | Modification process using N-chloro-thiosulfonamide and rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-03-20 | — | — | US | claimed |
| US-4820780-A | Modification of rubber with N-chlorothio-sulfonamide | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-04-11 | — | — | US | claimed |
| US-4617347-A | CONVEYOR BELTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-10-14 | — | — | US | claimed |
| EP-0989171-A1 | N-halothio-amide-modified elastomers and their application as adhesives for precured elastomeric substrates | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-03-29 | — | — | EP | disclosed |
| EP-0733651-B1 | Process for preparation of N-halothiosulfonamide modified terpolymers | GOODYEAR TIRE & RUBBER (US) | 1999-09-01 | — | — | EP | disclosed |
| US-5756590-A | MIXING TERPOLYMER WITH HALOTHIOSULFONAMIDE AND INCLUDING A HYDROHALIC ACID ACCEPTOR; OZONE RESISTANT TIRE SIDEWALLS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| US-4804028-A | Non-staining vulcanized elastomeric composition and tires having sidewalls comprising said composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0240448-A2 | Non-staining vulcanized elastomeric composition and tires having sidewalls comprising said composition | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-10-07 | — | — | EP | disclosed |
| US-4617347-A | CONVEYOR BELTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-10-14 | — | — | US | disclosed |
| US-3970133-A | Chlorothio-sulfonamide-modified rubbery terpolymers and their blends | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-07-20 | — | — | US | disclosed |