Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11153547 | 0.83 | MEN1 (0.43) | HTTMEN1KMT2ANR3C2CA12 | |
| SCHEMBL8039423 | 0.79 | MEN1 (0.40) | HTTMEN1KMT2ANR3C2CA12 | |
| SCHEMBL8028854 | 0.78 | APOBEC3G (0.47) | KMT2ACA12CA9ALDH1A1PKM | |
| SCHEMBL27395569 | 0.75 | CDK1 (0.40) | HTTMEN1KMT2ANR3C2CA12 | |
| SCHEMBL8042387 | 0.74 | CA12 (0.60) | HTTMEN1KMT2ACA12CA9 | |
| SCHEMBL1704542 | 0.70 | PKM (0.50) | HTTMEN1KMT2ANR3C2CA12 | |
| SCHEMBL2513199 | 0.70 | NR3C2 (0.44) | HTTMEN1KMT2ANR3C2CA12 | |
| SCHEMBL8052348 | 0.70 | MEN1 (0.36) | HTTMEN1KMT2ANR3C2CA12 | |
| SCHEMBL11381733 | 0.70 | MEN1 (0.34) | HTTMEN1KMT2ANR3C2CA12 | |
| SCHEMBL11379025 | 0.70 | MEN1 (0.36) | HTTMEN1KMT2ANR3C2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0989171-A1 | N-halothio-amide-modified elastomers and their application as adhesives for precured elastomeric substrates | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-03-29 | — | — | EP | disclosed |
| EP-0733651-B1 | Process for preparation of N-halothiosulfonamide modified terpolymers | GOODYEAR TIRE & RUBBER (US) | 1999-09-01 | — | — | EP | disclosed |
| US-5756590-A | MIXING TERPOLYMER WITH HALOTHIOSULFONAMIDE AND INCLUDING A HYDROHALIC ACID ACCEPTOR; OZONE RESISTANT TIRE SIDEWALLS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0733651-A1 | Process for preparation of N-halothiosulfonamide modified terpolymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-09-25 | — | — | EP | disclosed |