⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448691 | 0.85 | — | — | |
| SCHEMBL11571285 | 0.81 | CA1 (0.35) | — | |
| SCHEMBL11458047 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL7046706 | 0.75 | VCAM1 (0.36) | — | |
| SCHEMBL9161061 | 0.75 | CA1 (0.60) | — | |
| SCHEMBL43035 | 0.73 | — | — | |
| SCHEMBL381097 | 0.72 | CA1 (0.56) | — | |
| SCHEMBL972004 | 0.72 | — | — | |
| SCHEMBL667530 | 0.72 | CA1 (0.47) | — | |
| SCHEMBL7672679 | 0.71 | CA1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55092366-A | — | — | None | — | — | JP | disclosed |
| US-20240400564-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | SYNDAX PHARMACEUTICALS, INC. | 2024-12-05 | — | — | US | disclosed |
| EP-4463450-A1 | FUSED HETEROARYL HYDROXAMATES AS STING AGONISTS | Bisichem Co., Ltd. (KR) | 2024-11-20 | — | — | EP | disclosed |
| US-20240368075-A1 | Synthesis of N,N-Dialkyl, -Dialkenyl, -Dialkynyl, and Related Cyclics, Sulfamoyl Fluoride Compounds Using Hydrogen Fluoride | SES HOLDINGS PTE. LTD. (SG) | 2024-11-07 | — | — | US | disclosed |
| CN-118510770-A | Fused heteroaryl hydroxamic acids as STING agonists | 比西切姆有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-118496238-A | Macrocyclic compound, preparation method and application thereof, and pharmaceutical composition | 南京得恒医药科技有限公司 | 2024-08-16 | — | — | CN | disclosed |
| EP-4363400-A1 | SYNTHESIS OF N,N-DIALKYL, -DIALKENYL, -DIALKYNYL, AND RELATED CYCLICS, SULFAMOYL FLUORIDE COMPOUNDS USING HYDROGEN FLUORIDE | SES Holdings Pte. Ltd. (SG) | 2024-05-08 | — | — | EP | disclosed |
| CN-117956992-A | MENIN-MLL interaction inhibitors | 赛达克斯制药股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117682972-B | Organic compound containing sulfonamide group and fluorinated group and application thereof | 安徽盟维新能源科技有限公司 | 2024-04-30 | — | — | CN | disclosed |
| EP-4337203-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | Syndax Pharmaceuticals, Inc. (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-0009054-A1 | N-Pyrazinecarbonyl-N'-substituted-sulfamoyl-guanidine and processes for preparing same | MERCK & CO. INC. (US) | 1980-04-02 | — | — | EP | disclosed |
| US-4183937-A | Blood pressure lowering benzoquinolizines | JOHN WYETH & BROTHER LIMITED (GB) | 1980-01-15 | — | — | US | disclosed |
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |
| US-4148659-A | NONSILVER PHOTOGRAPHY | AGFA-GEVAERT N.V. (BE) | 1979-04-10 | — | — | US | disclosed |
| US-4115573-A | N-pyrazinecarbonyl-N'-substituted-sulfamoylguanidine and processes for preparing same | MERCK & CO., INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4066778-A | ANTIBACTERIAL, ANTIPROTAZOA, ANTHELMINTIC | CIBA-GEIGY CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
| US-4044151-A | Sulfamidophenethanolamine therapeutic process | MEAD JOHNSON & COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-3976778-A | ANTHELMINTIC, BACTERICIDE, ANTIPROTOZOA | CIBA-GEIGY CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3951958-A | VAGINOTROPIC | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |
| US-3951959-A | VAGINOTROPIC | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-04-20 | — | — | US | disclosed |