SCHEMBL8039504

SCHEMBL8039504

CCNc1nc(N)nc(NCCO)n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
GAA P10253 3/20 0.47
MEN1 O00255 2/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
MCL1 Q07820 2/20 0.46
LMNA P02545 2/20 0.45
SLC29A1 Q99808 1/20 0.45
CYP2C19 P33261 3/20 0.44
CYP1A2 P05177 2/20 0.44
ALDH1A1 P00352 1/20 0.44
RECQL P46063 1/20 0.43
HRH4 Q9H3N8 1/20 0.43
KDM4E B2RXH2 2/20 0.42
NPC1 O15118 1/20 0.42
NFKB1 P19838 1/20 0.42
CASP3 P42574 1/20 0.42
CDK9 P50750 1/20 0.42
RAB9A P51151 1/20 0.42
CDK5 Q00535 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1031350 0.90 KMT2A (0.50) KMT2AGAAMEN1MAPK1MCL1
SCHEMBL18062210 0.88 RECQL (0.48) KMT2AGAAMEN1MAPK1MCL1
SCHEMBL21325584 0.87 TLR8 (0.49) KMT2AGAAMEN1MAPK1L3MBTL1
SCHEMBL1033545 0.86 KMT2A (0.50) KMT2AGAAMEN1MAPK1MCL1
SCHEMBL7076660 0.85 LMNA (0.58) KMT2AGAAMEN1MAPK1L3MBTL1
SCHEMBL14725038 0.85 SLC29A1 (0.63) KMT2AGAAMEN1MAPK1LMNA
SCHEMBL16543336 0.84 CYP1A2 (0.61) KMT2AGAAMEN1L3MBTL1MCL1
SCHEMBL6835059 0.83 LMNA (0.56) KMT2AGAAMEN1MAPK1L3MBTL1
SCHEMBL18465161 0.83 KMT2A (0.50) KMT2AGAAMEN1MAPK1MCL1
SCHEMBL8467706 0.82 RECQL (0.44) KMT2AGAAMEN1MAPK1MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6124381-A CURING ACCELERATOR IS A 2-((MONO- OR DI-ALKYL)AMINO, MORPHOLINO, PIPERIDINO, METHYL OR PHENYL)-4,6-SUBSTITUTED DIAMINO-1,3,5-TRIAZINE OF GIVEN FORMULA; POT LIFE, STORAGE STABILITY, AND WORKABILITY NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-26 US disclosed
EP-0834523-A1 EPOXY/ACID ANHYDRIDE COMPOSITION NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1998-04-08 EP disclosed