SCHEMBL1033545

SCHEMBL1033545

Nc1nc(N)nc(NCCO)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
GAA P10253 2/20 0.50
MEN1 O00255 1/20 0.50
MAPK1 P28482 1/20 0.50
CYP2D6 P10635 1/20 0.48
CYP2C19 P33261 1/20 0.48
SLC29A1 Q99808 4/20 0.46
RECQL P46063 1/20 0.46
MCL1 Q07820 1/20 0.46
HRH4 Q9H3N8 3/20 0.45
CDK1 P06493 1/20 0.44
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
GBA1 P04062 1/20 0.40
POLB P06746 1/20 0.40
CCNA2 P20248 3/20 0.40
CDK2 P24941 3/20 0.40
CCNA1 P78396 3/20 0.40
EGFR P00533 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1031350 0.95 KMT2A (0.50) KMT2AGAAMEN1MAPK1CYP2D6
SCHEMBL18062210 0.93 RECQL (0.48) KMT2AGAAMEN1MAPK1CYP2D6
SCHEMBL8467706 0.87 RECQL (0.44) KMT2AGAAMEN1MAPK1CYP2D6
SCHEMBL6638595 0.86 NUDT1 (0.49) KMT2AGAAMEN1MAPK1SLC29A1
SCHEMBL14389373 0.86 KMT2A (0.52) KMT2AGAAMEN1MAPK1CYP2D6
SCHEMBL8039504 0.86 KMT2A (0.47) KMT2AGAAMEN1MAPK1CYP2D6
SCHEMBL29391675 0.86 KMT2A (0.56) KMT2AGAAMEN1MAPK1CYP2D6
SCHEMBL380440 0.85 CA1 (0.47) HRH4CA1CA2CA9ALDH1A1
SCHEMBL6643247 0.85 KCNH3 (0.49) KMT2ASLC29A1CDK1CA1CA2
SCHEMBL18465161 0.84 KMT2A (0.50) KMT2AGAAMEN1MAPK1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115467044-B Preparation method of melamine fiber and obtained melamine fiber 中国科学院成都有机化学有限公司 2024-06-14 CN claimed
CN-116285375-A Low-smoke halogen-free ultra-high voltage cable sheath material, cable and preparation method thereof 远东电缆有限公司 2023-06-23 CN claimed
CN-114316428-B Halogen-free flame-retardant polypropylene composition and preparation and application thereof 上海金发科技发展有限公司 2023-05-30 CN claimed
CN-113493679-B Formaldehyde-free feather protein adhesive and preparation method thereof 南京林业大学 2023-01-06 CN claimed
CN-115467044-A Preparation method of melamine fiber and obtained melamine fiber 中国科学院成都有机化学有限公司 2022-12-13 CN claimed
CN-114316428-A Halogen-free flame-retardant polypropylene composition and preparation and application thereof 上海金发科技发展有限公司 2022-04-12 CN claimed
CN-109504343-B Formaldehyde-free bean gum and preparation method thereof 北京林业大学 2022-01-28 CN claimed
CN-113493679-A Formaldehyde-free feather protein adhesive and preparation method thereof 南京林业大学 2021-10-12 CN claimed
CN-109627483-B Preparation method of melamine rigid closed-cell foam 四川金象赛瑞化工股份有限公司 2021-08-10 CN claimed
CN-112679863-A Flame-retardant polypropylene composite material and preparation method and application thereof 广东金发科技有限公司 2021-04-20 CN claimed
WO-2002048248-A2 MODIFIED INORGANIC PARTICLES AGROLINZ MELAMIN GMBH (AT) 2002-06-20 WO claimed
WO-2002048270-A1 POLYMER MODIFIED INORGANIC PARTICLES AGROLINZ MELAMIN GMBH (AT) 2002-06-20 WO claimed
WO-2002048261-A2 METHOD FOR CURING AMINOPLAST RESINS AGROLINZ MELAMIN GMBH (AT) 2002-06-20 WO claimed
EP-0355760-B1 Continuous production of aqueous solutions of melamine-formaldehyde precondensates BASF AG (DE) 1994-11-02 EP claimed
US-4996289-A Metering; continuous mixing BASF AKTIENGESELLSCHAFT (DE) 1991-02-26 US claimed
EP-0221330-B1 FOAMS AND FIBRES MADE OF MELAMINE RESINS HAVING AN INCREASED RIGIDITY BASF Aktiengesellschaft (DE) 1991-01-02 EP claimed
EP-0390278-A1 3-(1,3-oxazolidinyl)-s-triazine DSM N.V. (NL) 1990-10-03 EP claimed
EP-0355760-A2 Continuous production of aqueous solutions of melamine-formaldehyde precondensates BASF Aktiengesellschaft (DE) 1990-02-28 EP claimed
US-4797340-A Dry electrophotographic toner comprising graft copolymer FUJI XEROX CO., LTD. (JP) 1989-01-10 US claimed
EP-0221330-A1 Foams and fibres made of melamine resins having an increased rigidity BASF Aktiengesellschaft (DE) 1987-05-13 EP claimed