Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 15/20 | 0.50 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | BMP1 | P13497 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412306 | 0.79 | BMP1 (0.54) | BMP1CNR2 | |
| SCHEMBL6411529 | 0.79 | BMP1 (0.53) | BMP1CNR2 | |
| SCHEMBL8041132 | 0.74 | BMP1 (0.58) | BMP1CNR2 | |
| SCHEMBL6417009 | 0.74 | BMP1 (0.53) | BMP1CNR2 | |
| SCHEMBL8037719 | 0.70 | BMP1 (0.56) | BMP1CNR2 | |
| SCHEMBL8027629 | 0.70 | BMP1 (0.56) | BMP1CNR2 | |
| SCHEMBL8038049 | 0.69 | BMP1 (0.62) | BMP1CNR2 | |
| SCHEMBL8038085 | 0.69 | BMP1 (0.69) | BMP1CNR2 | |
| SCHEMBL8027595 | 0.69 | BMP1 (0.69) | BMP1CNR2 | |
| SCHEMBL8044091 | 0.68 | BMP1 (0.45) | BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124329-A | AN ENZYME INHIBITOR FOR THE TREATMENT OR PROPHYLAXIS OF TISSUE BREAKDOWN, FOR EXAMPLE RHEUMATOID ARTHRITIS, OSTEOPOROSIS, PERIODONTITIS, GINGIVITIS, CORNEAL EPIDERMAL OR GASTRIC ULCERATION, AND TUMOR, MULTIPLE SCLEROSIS | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2000-09-26 | — | — | US | disclosed |
| EP-0766664-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2000-04-05 | — | — | EP | disclosed |
| EP-0766664-A2 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-04-09 | — | — | EP | disclosed |
| WO-1995035275-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-12-28 | — | — | WO | disclosed |