Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.45 |
| ▸ | DRD2 | P14416 | 4/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028794 | 0.88 | PPARG (0.69) | PPARGHDAC1HDAC6TBXA2RALOX5AP | |
| SCHEMBL4532827 | 0.86 | PPARG (0.68) | PPARGHDAC1HDAC6KDM4ETBXA2R | |
| SCHEMBL8036202 | 0.84 | PPARG (0.65) | PPARGKDM4ECNR2TBXA2RDRD2 | |
| SCHEMBL8035322 | 0.82 | PPARG (0.65) | PPARGKDM4E | |
| SCHEMBL4540880 | 0.81 | PPARG (0.50) | PPARGKDM4ECNR2TBXA2RDRD2 | |
| SCHEMBL4565571 | 0.80 | PPARG (1.00) | PPARG | |
| SCHEMBL8037666 | 0.80 | PPARG (1.00) | PPARG | |
| SCHEMBL8025911 | 0.76 | KDM4E (0.70) | PPARGHDAC1HDAC6KDM4ETBXA2R | |
| SCHEMBL2100541 | 0.75 | KDM4E (0.55) | PPARGKDM4ECNR2TBXA2RDRD2 | |
| SCHEMBL408881 | 0.75 | KDM4E (0.53) | HDAC1HDAC6KDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |