Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.45 |
| ▸ | DRD2 | P14416 | 5/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4532827 | 0.83 | PPARG (0.68) | PPARGKDM4ETBXA2RDRD2 | |
| SCHEMBL8035322 | 0.82 | PPARG (0.65) | PPARGKDM4E | |
| SCHEMBL8036202 | 0.82 | PPARG (0.65) | PPARGKDM4ETBXA2RDRD2CNR2 | |
| SCHEMBL8039653 | 0.81 | PPARG (0.66) | PPARGKDM4ETBXA2RDRD2CNR2 | |
| SCHEMBL8025911 | 0.73 | KDM4E (0.70) | PPARGKDM4ETBXA2RDRD2 | |
| SCHEMBL2100541 | 0.73 | KDM4E (0.55) | PPARGKDM4ETBXA2RDRD2CNR2 | |
| SCHEMBL4535196 | 0.71 | PPARG (0.72) | PPARGTBXA2RCCR2 | |
| SCHEMBL2161533 | 0.70 | KDM4E (0.68) | PPARGKDM4E | |
| SCHEMBL19987318 | 0.70 | KDM4E (0.68) | PPARGKDM4ECNR2 | |
| SCHEMBL8036225 | 0.70 | PPARG (0.65) | PPARGKDM4ETBXA2RDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |