Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 2/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8039543 | 1.00 | ABCC1 (0.45) | ABCC1SRD5A1KDM4EHTTKMT2A | |
| SCHEMBL8039706 | 1.00 | ABCC1 (0.45) | ABCC1SRD5A1KDM4EHTTKMT2A | |
| SCHEMBL8038300 | 1.00 | ABCC1 (0.45) | ABCC1SRD5A1KDM4EHTTKMT2A | |
| SCHEMBL8039687 | 0.99 | SRD5A1 (0.43) | ABCC1SRD5A1KDM4EHTTKMT2A | |
| SCHEMBL8041066 | 0.90 | TSHR (0.54) | KDM4EHTTKMT2AALDH1A1TSHR | |
| SCHEMBL8037924 | 0.90 | TSHR (0.54) | KDM4EHTTKMT2AALDH1A1TSHR | |
| SCHEMBL8037888 | 0.89 | TSHR (0.55) | KDM4EHTTKMT2AALDH1A1TSHR | |
| SCHEMBL8041280 | 0.88 | SERPINE1 (0.46) | KDM4EKMT2AALDH1A1ADRB1ADRB3 | |
| SCHEMBL8027780 | 0.88 | ABCC1 (0.47) | ABCC1SRD5A1KDM4EKMT2AMEN1 | |
| SCHEMBL8041170 | 0.87 | KMT2A (0.47) | ABCC1KDM4EKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |
| US-5808144-A | ANTIALLERGENS | TEIJIN LIMITED (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0806412-A1 | BENZENE DERIVATIVES | TEIJIN LIMITED (JP) | 1997-11-12 | — | — | EP | disclosed |