Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 6/20 | 0.46 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027780 | 0.88 | ABCC1 (0.47) | KDM4EHSD17B10KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8038300 | 0.88 | ABCC1 (0.45) | KDM4EKMT2AALDH1A1NPSR1ADRB1 | |
| SCHEMBL8039543 | 0.88 | ABCC1 (0.45) | KDM4EKMT2AALDH1A1NPSR1ADRB1 | |
| SCHEMBL8039714 | 0.88 | ABCC1 (0.45) | KDM4EKMT2AALDH1A1NPSR1ADRB1 | |
| SCHEMBL8039706 | 0.88 | ABCC1 (0.45) | KDM4EKMT2AALDH1A1NPSR1ADRB1 | |
| SCHEMBL8039687 | 0.87 | SRD5A1 (0.43) | KDM4EKMT2AALDH1A1NPSR1ADRB1 | |
| SCHEMBL8037924 | 0.81 | TSHR (0.54) | KDM4EHSD17B10KMT2AALDH1A1NPSR1 | |
| SCHEMBL8041066 | 0.81 | TSHR (0.54) | KDM4EHSD17B10KMT2AALDH1A1NPSR1 | |
| SCHEMBL8037972 | 0.81 | ALDH1A1 (0.44) | KDM4EHSD17B10KMT2AALDH1A1NPSR1 | |
| SCHEMBL8037888 | 0.80 | TSHR (0.55) | KDM4EHSD17B10KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806412-B1 | BENZENE DERIVATIVES | TEIJIN LTD (JP) | 2000-04-05 | — | — | EP | disclosed |