Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30525289 | 0.86 | HDAC3 (0.47) | HSD11B1HDAC3HDAC1HDAC2HPGD | |
| SCHEMBL5695491 | 0.84 | HDAC3 (0.49) | HSD11B1HDAC3HDAC1HDAC2HPGD | |
| SCHEMBL2286036 | 0.84 | HPGD (0.49) | HSD11B1HDAC3HDAC1HDAC2HPGD | |
| SCHEMBL29388635 | 0.84 | HPGD (0.49) | HSD11B1HDAC3HDAC1HDAC2HPGD | |
| SCHEMBL1567147 | 0.84 | HDAC3 (0.46) | HSD11B1HDAC3HDAC1HDAC2HPGD | |
| SCHEMBL430259 | 0.84 | HDAC3 (0.49) | HSD11B1HDAC3HDAC1HDAC2HPGD | |
| SCHEMBL229558 | 0.84 | HPGD (0.49) | HSD11B1HDAC3HDAC1HDAC2HPGD | |
| SCHEMBL4934593 | 0.84 | HDAC3 (0.49) | HSD11B1HDAC3HDAC1HDAC2HPGD | |
| SCHEMBL30887999 | 0.84 | HDAC3 (0.49) | HSD11B1HDAC3HDAC1HDAC2HPGD | |
| SCHEMBL230023 | 0.84 | HPGD (0.49) | HSD11B1HDAC3HDAC1HDAC2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656438-A | 5, 7-dihydroxy-2, 2-dimethyl-6-acetyl-chroman and synthesis method and application thereof | 广西壮族自治区中医药研究院 | 2022-06-24 | — | — | CN | disclosed |
| CN-114656438-A | 5, 7-dihydroxy-2, 2-dimethyl-6-acetyl-chroman and synthesis method and application thereof | 广西壮族自治区中医药研究院 | 2022-06-24 | — | — | CN | disclosed |
| US-20130295261-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2013-11-07 | — | — | US | disclosed |
| WO-2008020438-A2 | BENZOTHIAZOLYL THIENOPYRIDINE DERIVATIVES AND USES THEREOF | RIMONYX PHARMACEUTICALS LTD (IL) | 2008-02-21 | — | — | WO | disclosed |
| WO-2000076990-A1 | NEW COMPOUNDS | ASTRAZENECA AB (SE) | 2000-12-21 | — | — | WO | disclosed |