SCHEMBL8040136

SCHEMBL8040136

C=CC(=O)OCCCCCCc1cccc2ccccc12

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.51
ALDH1A1 P00352 3/20 0.51
CYP3A4 P08684 1/20 0.51
THRB P10828 2/20 0.48
THRA P10827 1/20 0.47
CDYL Q9Y232 1/20 0.43
MTNR1A P48039 3/20 0.43
SLC16A3 O15427 1/20 0.43
MTNR1B P49286 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MCL1 Q07820 2/20 0.41
KDM4E B2RXH2 1/20 0.41
HPGD P15428 1/20 0.41
TP53 P04637 2/20 0.40
HIF1A Q16665 2/20 0.40
HSD17B10 Q99714 1/20 0.40
TGM2 P21980 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8028267 1.00 TSHR (0.51) TSHRALDH1A1CYP3A4THRBTHRA
SCHEMBL29503714 0.99 THRB (0.49) TSHRALDH1A1CYP3A4THRBTHRA
SCHEMBL8038228 0.99 THRB (0.49) TSHRALDH1A1CYP3A4THRBTHRA
SCHEMBL8041649 0.94 THRB (0.50) TSHRALDH1A1CYP3A4THRBTHRA
SCHEMBL68668 0.89 THRB (0.53) TSHRALDH1A1THRBCDYLMTNR1A
SCHEMBL29384579 0.89 THRB (0.53) TSHRALDH1A1THRBCDYLMTNR1A
SCHEMBL28989666 0.88 THRB (0.48) TSHRALDH1A1CYP3A4THRBTHRA
SCHEMBL19360472 0.87 ALDH1A1 (0.49) TSHRALDH1A1CYP3A4THRBCDYL
SCHEMBL29503672 0.87 THRB (0.49) TSHRALDH1A1CYP3A4THRBTHRA
SCHEMBL28989633 0.83 KMT2A (0.56) TSHRALDH1A1CYP3A4THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO claimed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO disclosed