SCHEMBL8040137

SCHEMBL8040137

C=CC(=O)OCCCCCCc1ccc2ccccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.52
HDAC8 Q9BY41 2/20 0.52
ALDH1A1 P00352 1/20 0.51
CYP3A4 P08684 1/20 0.51
TSHR P16473 1/20 0.51
THRB P10828 4/20 0.51
CYP1A2 P05177 1/20 0.51
NAAA Q02083 1/20 0.44
HCAR2 Q8TDS4 1/20 0.43
SIGMAR1 Q99720 1/20 0.42
PDPK1 O15530 1/20 0.42
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
HDAC9 Q9UKV0 1/20 0.42
HDAC5 Q9UQL6 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28989636 1.00 HDAC1 (0.52) HDAC1HDAC8ALDH1A1CYP3A4TSHR
SCHEMBL28989670 0.99 THRB (0.52) HDAC1HDAC8ALDH1A1CYP3A4TSHR
SCHEMBL28989829 0.96 THRB (0.50) HDAC1HDAC8ALDH1A1CYP3A4TSHR
SCHEMBL28989706 0.95 THRB (0.51) HDAC1HDAC8ALDH1A1CYP3A4TSHR
SCHEMBL5270056 0.94 THRB (0.54) HDAC1HDAC8ALDH1A1CYP3A4TSHR
SCHEMBL5267795 0.89 THRB (0.56) HDAC1HDAC8ALDH1A1CYP3A4TSHR
SCHEMBL28989632 0.85 TSHR (0.50) HDAC1HDAC8ALDH1A1CYP3A4TSHR
SCHEMBL19456882 0.84 TSHR (0.59) ALDH1A1CYP3A4TSHRTHRBNAAA
SCHEMBL19456904 0.84 TSHR (0.59) ALDH1A1CYP3A4TSHRTHRBNAAA
SCHEMBL28989833 0.84 TSHR (0.47) ALDH1A1CYP3A4TSHRTHRBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO claimed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO disclosed