SCHEMBL5267795

SCHEMBL5267795

C=CC(=O)OCCc1ccc2ccccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.56
CYP1A2 P05177 1/20 0.49
APP P05067 1/20 0.46
PDPK1 O15530 1/20 0.46
HCAR2 Q8TDS4 1/20 0.45
ALDH1A1 P00352 3/20 0.45
TP53 P04637 3/20 0.45
HSD17B10 Q99714 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
EGFR P00533 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.45
PKM P14618 1/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
ALOX12 P18054 1/20 0.45
JAK1 P23458 1/20 0.45
MAPK1 P28482 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5270056 0.91 THRB (0.54) THRBCYP1A2PDPK1HCAR2ALDH1A1
SCHEMBL28989670 0.90 THRB (0.52) THRBCYP1A2PDPK1HCAR2ALDH1A1
SCHEMBL8040137 0.89 HDAC1 (0.52) THRBCYP1A2PDPK1HCAR2ALDH1A1
SCHEMBL28989636 0.89 HDAC1 (0.52) THRBCYP1A2PDPK1HCAR2ALDH1A1
SCHEMBL18194816 0.86 THRB (0.46) THRBAPPHCAR2ALDH1A1TP53
SCHEMBL28989706 0.86 THRB (0.51) THRBCYP1A2PDPK1HCAR2ALDH1A1
SCHEMBL22920624 0.85 APP (0.49) CYP1A2APPPDPK1HCAR2HDAC1
SCHEMBL28989829 0.85 THRB (0.50) THRBCYP1A2HCAR2ALDH1A1TP53
SCHEMBL845505 0.84 TGM2 (0.49) THRBCYP1A2PDPK1HCAR2ALDH1A1
SCHEMBL30715271 0.84 TGM2 (0.49) THRBCYP1A2PDPK1HCAR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119899310-A Acrylate polymer, ultraviolet-curable adhesive composition and polarizer 恒美光电股份有限公司 2025-04-29 CN claimed
WO-2007110387-A1 PHOTO-CURABLE RESINS AND RESIN COMPOSITIONS WITH VERY HIGH REFRACTIVE INDICES FOR APPLICATION IN PLASIC OPTICS SEEREAL TECHNOLOGIES S.A. (DE) 2007-10-04 WO claimed
EP-1840652-A1 Photo-curable resins and resin compositions with very high refractive indices for application in plastic optics SeeReal Technologies S.A. (LU) 2007-10-03 EP claimed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO claimed
CN-119899310-A Acrylate polymer, ultraviolet-curable adhesive composition and polarizer 恒美光电股份有限公司 2025-04-29 CN disclosed
CN-119065045-A Optical laminate and image display device using the same 日东电工株式会社 2024-12-03 CN disclosed
WO-2007110387-A1 PHOTO-CURABLE RESINS AND RESIN COMPOSITIONS WITH VERY HIGH REFRACTIVE INDICES FOR APPLICATION IN PLASIC OPTICS SEEREAL TECHNOLOGIES S.A. (DE) 2007-10-04 WO disclosed
WO-2007110387-A1 PHOTO-CURABLE RESINS AND RESIN COMPOSITIONS WITH VERY HIGH REFRACTIVE INDICES FOR APPLICATION IN PLASIC OPTICS SEEREAL TECHNOLOGIES S.A. (DE) 2007-10-04 WO disclosed
EP-1840652-A1 Photo-curable resins and resin compositions with very high refractive indices for application in plastic optics SeeReal Technologies S.A. (LU) 2007-10-03 EP disclosed
EP-1840652-A1 Photo-curable resins and resin compositions with very high refractive indices for application in plastic optics SeeReal Technologies S.A. (LU) 2007-10-03 EP disclosed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 WO disclosed