Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.64 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.56 |
| ▸ | TFEB | P19484 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9478629 | 0.91 | LMNA (0.59) | LMNAMAPTKMT2AMEN1PLIN1 | |
| SCHEMBL7414397 | 0.91 | LMNA (0.59) | LMNAMAPTKMT2AMEN1PLIN1 | |
| SCHEMBL11002399 | 0.90 | MAPT (0.61) | LMNAMAPTKMT2AMEN1PLIN1 | |
| SCHEMBL10353470 | 0.90 | MAPT (0.61) | LMNAMAPTKMT2AMEN1PLIN1 | |
| SCHEMBL11763791 | 0.85 | KDM4E (0.59) | LMNAMAPTKMT2AMEN1PLIN1 | |
| SCHEMBL11763787 | 0.85 | KDM4E (0.59) | LMNAMAPTKMT2AMEN1PLIN1 | |
| SCHEMBL998236 | 0.85 | LMNA (0.64) | LMNAMAPTKMT2AMEN1PLIN1 | |
| SCHEMBL10756378 | 0.85 | KMT2A (0.86) | LMNAMAPTKMT2AMEN1PLIN1 | |
| SCHEMBL15026368 | 0.85 | KMT2A (0.86) | LMNAMAPTKMT2AMEN1PLIN1 | |
| SCHEMBL10756388 | 0.85 | KMT2A (0.86) | LMNAMAPTKMT2AMEN1PLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440324-B1 | Substituted beta-diketones and their use in the treatment of inflammatory bowel disease | ORION YHTYMAE OY (FI) | 2000-04-12 | — | — | EP | disclosed |