Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053183 | 0.73 | ACHE (0.32) | HTR2AHTR2CHTR2BCHRNB2CHRNA4 | |
| SCHEMBL9141944 | 0.71 | HTR2A (0.36) | HTR2AHTR2CHTR2B | |
| Lithium SCHEMBL9141948 | 0.71 | HTR2A (0.36) | HTR2AHTR2CHTR2B | |
| SCHEMBL27860447 | 0.71 | TSHR (0.33) | HTR2AHTR2CHTR2BCHRNB2CHRNA4 | |
| SCHEMBL27876782 | 0.71 | TSHR (0.33) | HTR2AHTR2CHTR2BCHRNB2CHRNA4 | |
| SCHEMBL1453773 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL3627746 | 0.69 | HTR2A (0.35) | HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL3627842 | 0.69 | HTR2A (0.35) | HTR2AHTR2CHTR2B | |
| SCHEMBL15617549 | 0.69 | TSHR (0.32) | MAP3K14 | |
| SCHEMBL2973533 | 0.68 | CA12 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582195-B1 | Process for the preparation of polymers using specific metallocenes | TARGOR GMBH (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6087292-A | Metallocene catalysts comprising indenyl ligands substituted with electronegative groups | TANGOR GMBH (DE) | 2000-07-11 | — | — | US | disclosed |
| US-5763542-A | Process for the preparation of an olefin polymer using specific metallocenes | TARGOR GMBH (DE) | 1998-06-09 | — | — | US | disclosed |
| US-5504232-A | Process for the preparation of an olefin polymer using specific metallocenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |
| EP-0582195-A1 | Process for the preparation of polymers using specific metallocenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-09 | — | — | EP | disclosed |