Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040663 | 0.95 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL213640 | 0.92 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL8040698 | 0.91 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL8040656 | 0.88 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL215649 | 0.86 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL213154 | 0.86 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL8051577 | 0.86 | PTGS2 (0.46) | PTGS2PTGS1 | |
| SCHEMBL8040707 | 0.85 | ALOX5 (0.40) | PTGS2PTGS1 | |
| SCHEMBL8302968 | 0.84 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL8053210 | 0.82 | PTGS2 (0.47) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808305-B1 | 3,4-DIARYL SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-05-03 | — | — | EP | claimed |
| EP-0808305-B1 | 3,4-DIARYL SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-05-03 | — | — | EP | disclosed |
| US-5596008-A | ANALGESICS, ANTIARTHRITIC | G. D. SEARLE & CO. (US) | 1997-01-21 | — | — | US | disclosed |